Health Canada Confirms Undisclosed Presence of DNA Sequence in Pfizer Shot

 Health Canada has verified that the Pfizer COVID-19 vaccination contains a Simian Virus 40 (SV40) DNA sequence, which the manufacturer had not previously revealed. Regarding the relevance of the discovery, scientists are divided; some believe it may cause cancer, while others believe it presents little to no risk.

Health Canada informed The Epoch Times via email that it "expects sponsors to identify any biologically functional DNA sequences within a plasmid (such as an SV40 enhancer) at the time of submission."

"Although the full DNA sequence of the Pfizer plasmid was provided at the time of initial filing, the sponsor did not specifically identify the SV40 sequence."

According to the regulator, "it was possible for Health Canada to confirm the presence of the enhancer based on the plasmid DNA sequence submitted by Pfizer against the published SV40 enhancer sequence" following the announcement earlier this year by scientists Kevin McKernan and Dr. Phillip J. Buckhaults regarding the presence of SV40 enhancers in the vaccines.

After finding plasmid DNA in the mRNA COVID-19 injections, both scientists caused a stir and issued a warning that this may potentially change the human genome. The importance of an SV40 sequence, which is utilized as an enhancer to induce gene transcription during the vaccine manufacturing process, being present in the doses, however, concerns the two to varying degrees.

A prior version of the polio vaccine had the oncogenic DNA virus Simian Virus 40, a polyomavirus, but it was eliminated because of worries about its connection to cancer. The SV40 virus was discovered to be present in the monkey kidney cells used to cultivate the polio vaccine, which was administered in the late 1950s and early 1960s.

The director of the University of South Carolina's Cancer Genetics Lab and professor of cancer genomics, Dr. Buckaults, has attempted to allay worries regarding the SV40 enhancers by stating that while they do present a "small [cancer] hazard, so do all the other pieces of plasmid DNA."

The SV40 enhancer sequence, which is derived from SV40, is a "standard bit of molecular biology engineering to achieve high-level expression of the Neo resistance marker," according to Dr. Buckhaults on social media, adding that it has been "used for decades."

The SV40 enhancer gene was included in the vaccinations since it is a part of the plasmid that is used for vaccine mRNA amplification, according to Dr. Patrick Provost, a professor in the Department of Microbiology, Infectious Diseases and Immunology at the Faculty of Medicine at Laval University.

The risk associated with the vaccine's SV40 enhancers, according to Dr. Provost, is that they might integrate into a cell's DNA genome. "All it takes is a single integration at the wrong place in a single cell to initiate a cancerous process and kill a person," he explained.

According to Dr. Provost, if DNases—which are designed to break down big DNA pieces into smaller ones—did not sufficiently degrade the plasmid DNA, the SV40 enhancer might still be present in the finished product. Given that the SV40 enhancer sequence is only 72 base pairs long and the average length of the degraded DNA fragments discovered by Dr. Buckhaults was 100 base pairs, he said the likelihood of discovering an intact, fully functional SV40 enhancer sequence in the mRNA vaccines is "relatively high, certainly not negligible."

The possibility that the contaminated DNA fragments in the vaccinations are coated in lipid nanoparticles, which may facilitate their distribution into human cells, is another concern brought up by Dr. Provost. The standards for contaminating DNA, which was determined for "naked" DNA that was not encapsulated in nanoparticles, he cautioned, might become "completely irrelevant."

Microbiologist Mr. McKernan made the initial discovery in April 2023 that the Pfizer monovalent and bivalent vaccinations contain the SV40 enhancer or promoter DNA. He discovered that Pfizer's COVID-19 vaccines included SV40 72bp enhancers and promoters by analyzing the nucleic acid makeup of four vials of the Moderna and Pfizer vaccines using a variety of techniques.

The SV40 promoter was "completely redundant" and "all risk, no reward," according to Mr. McKernan, because Pfizer's vaccines already contain an AmpR promoter similar to Moderna—which is used to drive the antibiotic resistance gene.

According to Mr. McKernan, even though the polio vaccines contained the entire 5 kb SV40 virus, the existence of SV40 promoters remained worrisome because of the possibility that they would integrate into human genomes close to oncogenes—genes that can cause cancer.